Last night, Jennifer Aniston stepped out to support her pal Courteney Cox at the Crystal + Lucy Awards, where the Cougar Town star was honored for her TV work. And the ladies – who got close as costars in Friends — will soon be working together again soon, Star has learned exclusively.

In the June 14 issue of Star — on sale now — we report that Jennifer may be known for her romantic comedies, but she’s switching genres for her new role: a part in Scream 4!

Jen will play a woman who’s killed off in the opening sequence, a trademark of the franchise — as a favor to BFF and Scream actress Courteney. The role will be similar to Drew Barrymore’s killer part in the first film.

“Scream has always been an important part of Courteney’s life, and she wanted Jennifer to be a part of the production,” an insider tells Star.

Courteney, her husband David Arquette and Neve Campbell will all reprise their roles in the next installment, which hits theatres in April 2011.